Fascinating. I'm thinking water colors, no? Regardless, this piece is wildly interesting, it communicates emotions, as the subject of the photo, this woman, seems confused, bewildered even, what at, that is the question. As for the medium itself, it's a wonderfully different departure from what you normally seem to do, and though a bit more... (I'm reluctant to use the word 'childish' because of it's usually negative connotation) but it seems appropriate because of the simpler nature of the work, despite that, I can see that it's very skillfully done. I've got no metaphorical commentary for this one, it's just fun and well done.
I have to do this scale and proportion thing for my graphic design class, and it involves lot of cutting... not looking forward to doing it, but I am looking forward to the outcome. Amazing work, as always! I love your stuff!